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uses of chloramphenicol
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uses of chloramphenicol

The duration for which Chloramphenicol remains effective usually varies according to the intended use and dosing regimen. Its use by mouth or by injection is only recommended when no other antibiotics work effectively. Risks involved outweigh potential benefits. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. This includes use as an eye ointment to treat conjunctivitis. Cet antibiotique peut être utilisé pour traiter la méningite, la peste, le choléra, la fièvre typhoïde uniquement lorsque les antibiotiques plus sûrs ne peuvent pas être employés. Do not start, stop, or change the dose of Chloramphenicol is an antibiotic not authorised for use in food-producing animals in the European Union (EU). chloramphenicol during labor. You must check Signs of an allergic reaction, like rash; Signs of infection like fever, chills, very bad. help if any of these side effects or any other side effects bother you or do not go away: These are not all of the side effects that may occur. D: Use in LIFE-THREATENING emergencies when no safer drug available. However, chloramphenicol should not be used for colds, flu, other virus infections, sore throats or other minor infections, or to prevent infections. In addition, chloramphenicol was found to have two other characteristics which promised to make it useful in the treatment of patients. We comply with the HONcode standard for trustworthy health information -, Chloramphenicol Oral, Intravenous, Injection. 1,000 mg /vial. It has been used for the selection/growth of positive bacterial cells. Snyder MJ, Woodward TE. If you have an allergy to chloramphenicol or any other part of chloramphenicol. Owing to resistance and safety concerns, this drug is no longer commonly used. Tell your doctor if you are breast-feeding. Chemical Class: Chloramphenicol (class) Uses for chloramphenicol. Some medicines may interact with the action of Chloramphenicol. Uses of Chloramphenicol for Dogs and Cats. However, chloramphenicol should not be used for colds, flu, other virus … with your doctor, nurse, pharmacist, or other health care provider. This medication treats only bacterial eye infections. Tell your doctor if you are pregnant or plan on getting pregnant. Biochemical effects. Chloramphenicol is available under the following different brand names: Chloramphenicol IV and Chloromyectin. 1. Chloramphénicol : antibiotique efficace sur divers types d'infections. It treats meningitis, cholera, plague and typhoid fever. However, chloramphenicol is a rarely used drug in the United States because of its known severe adverse effects, such as bone marrow toxicity and grey baby syndrome. 1978 Dec;59(12):889-94. This is not a list of all drugs or health problems that interact with chloramphenicol. Red eyes usually are caused by allergy, eye fatigue, over-wearing contact lenses or common eye infections such as pink eye. Chloramphenicol may be used in addition or as an alternative in patients not tolerating these drugs. Lors du traitement, il est recommandé de contrôler tous les deux jours la composition sanguine. Its use by mouth or by injection is only recommended when no other antibiotics work effectively. In recent years, fish have been widely recognised as a highly nutritious source of protein, essential fatty acids, micronutrients and minerals. However, chloramphenicol should not be used for colds, flu, other virus infections, sore throats or other minor infections, or to prevent infections. It is also occasionally prescribed in the form of ear drops to treat ear infections, and may be used in hospital to treat life-threatening infections, where it is generally given intravenously (via a vein). It is sometimes given with other antibiotics. Chloramphenicol is used to treat serious infections in different parts of the body. The recommended dose is two drops applied to the affected eye(s) every three hours. If you are allergic to chloramphenicol; any part of chloramphenicol; or any other drugs, foods, or substances. GUEST Bureau of Veterinary Medicine, Food and Drug Administration, Rockwill, Maryland, USA Chloramphenicol (CAP) is a prescription drug approved for use in dogs in the USA.Otic and ophthalmic CAP preparations have been approved for both dogs and cats.Initial approval chlor- amphenicol was in 1954 as 50 mg capsules for These brand names are discontinued in the U.S. Check with your You will need to talk about any risks to your baby. In young children a condition known as grey baby syndrome may occur which results in them having a swollen stomach and low blood pressure. 1978 Dec;59(12):889-94. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. However, many people have no side effects or only have minor side effects. PREGNANCY: There are no adequate studies done on chloramphenicol to determine safe and effective use in pregnant women. Therefore, blocking … Check with your doctor or pharmacist if you are not sure. It works by killing bacteria or preventing their growth. pharmacist if you are not sure. Chemical hazard agents – (Identify the category of the … Medically reviewed by Drugs.com. CHLORAMPHENICOL EXPLANATION Chloramphenicol is an antibiotic originally isolated from the soil bacterium Streptomyces venezuelae.It has the following chemical structure: Chloramphenicol was previously considered at the twelfth meeting of the Committee (Annex 1, reference 17), at which time it was determined that acceptable levels in food could not be established. If you are taking any drugs that can raise the chance of blood problems. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. We don't support your browser. Signs Chloramphenicol is an antibiotic useful for the treatment of a number of bacterial infections. Medicinal forms. 1. By mouth or by injection into a vein, it is used to treat meningitis, plague, cholera, and typhoid fever. These are available on prescription or to buy from pharmacies. This medication falls under the category of an antibiotic which works by reversibly binding to the 50S subunit of the ribosome of the bacterial cell. Chloramphenicol is a broad spectrum antibiotic used for treating a number of severe bacterial infections.This is also used as an eye ointment to treat conjunctivitis. It is the preferred drug for endophthalmitis caused by sensitive organisms. Chloramphenicol is commonly used in the laboratory environment at UW-Madison for selection of microbes (in vitro) that have been engineered to have resistance to chloramphenicol; and also as an antibiotic in live animals. USE OF CHLORAMPHENICOL IN THE UNITED STATES G.B. Chloramphenicol is available under the following different brand names: Chloramphenicol IV and Chloromyectin. This medication is used to treat bacterial eye infections. If you have anaemia, bone marrow problems, liver disease, or allergy from Chloramphenicol then inform your doctor before taking this medicine. Persons with typhoid fever usually have a sustained fever as high as 103° to 104° F (39° to 40° C). USE OF CHLORAMPHENICOL IN THE UNITED STATES G.B. Chloramphenicol may be acclimated as … Chloramphenicol is used to treat various bacterial infections in dogs and cats, including skin infections, wound infections, bone infections, central nervous system infections (encephalitis, meningitis), pneumonia, and intestinal infections (such as diarrhea). Le chloramphénicol pendant la grossesse engendre chez le fœtus des niveaux de médicament pouvant presque aller jusqu'aux niveaux maternels. It is sometimes given with other antibiotics. However, being produced by soil bacteria, it may occur in plants. Chloramphenicol is used to treat serious infections in different parts of the body. Chloramphenicol is used to treat serious infections in different parts of the body. There can be variation in the licensing of different medicines containing the same drug. This has happened in a baby born to a mother who got Chloramphenicol is widely distributed throughout the body, crosses the blood-brain barrier, and penetrates necrotic tissues and abscesses. There are many drugs that can do this. Aquaculture is an important component of the world’s food supply in both developed and developing countries. One of the most contagious infections to affect children and adults is conjunctivitis. Chloramphenicol is commonly used in the laboratory environment at UW-Madison for selection of microbes (in vitro) that have been engineered to have resistance to chloramphenicol; and also as an antibiotic in live animals. while you are pregnant. Please upgrade your browser or download modern browsers from here! Animal studies show risk and human studies not available or neither animal nor human studies done. Chloramphenicol is used to treat life-threatening infections, especially those caused by Haemophilus influenza, typhoid fever, and severe infections such as meninges inflammation and blood poisoning. It also comes as ear drops. Diploma In Dermatologist, Venereologist and Laparoscopy, MBBS. It is also occasionally prescribed in the form of ear drops to treat ear infections, and may be used in hospital to treat life-threatening infections, where it is generally given intravenously (via a vein). C: Use with caution if benefits outweigh risks. It is also effective against neurological infections, such as meningitis and encephalitis, and certain tick-borne diseases, such as … taken, how much, and when it happened. Conjunctivitis, also known as pink eye is an inflammation of the conjunctiva. Clark CH. Chloramphenicol is a broad spectrum antibiotic used for treating a number of severe bacterial infections.This is also used as an eye ointment to treat conjunctivitis. Therapeutic uses : Chloramphenicol use is restricted to life-threatening infections for which no alternatives exist. The clinical use of chloramphenicol. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. 1. I have used chloramphenicol to prevent bacterial infection in screening experiments and also in bioreactor experiment with filamentous fungi. Chloramphenicol should only be used for serious infections in which other medicines do not work. Snyder MJ, Woodward TE. Dosages of Chloramphenicol: Injectable solution. It is widely used for topical purposes in the form of eye and ENT drops and ointments. Is it safe to drive while on this medicine? Use during waking hours only. Mod Vet Pract. I guess, it is … Chloramphenicol injection is in a class of medications called antibiotics. Chloramphenicol comes as eye drops or eye ointment. Il a été introduit pour la première fois aux Etats-Unis en 1947. D: Use in LIFE-THREATENING emergencies when no safer drug available. Animals Chloramphenicol is a bacteriostatic, time-dependent acetamide antibiotic with a very broad spectrum of activity, including Gram-positive and Gram-negative aerobes, and anaerobes. Very bad and sometimes deadly reactions have happened in premature and newborn babies. Other brands: Chloromycetin, Chloromycetin Sodium Succinate, amoxicillin, doxycycline, triamcinolone, metronidazole, azithromycin, cephalexin, ciprofloxacin, clindamycin, levofloxacin, Bactrim. This may cause more chance of getting an infection, bleeding Chloramphenicol for dogs Veterinarians usually use it to treat skin infections, wound infections, bone infections, intestinal infections and pneumonia in cats and dogs. first show up after 3 to 4 days of getting chloramphenicol. Chloramphenicol - Get up-to-date information on Chloramphenicol side effects, uses, dosage, overdose, pregnancy, alcohol and more. It includes bone marrow suppression, diarrhoea and nausea. Its use by mouth or by injection is only recommended when no … When not to use A penicillin/cephalosporin is generally combined since most of these are mixed infections. Clinical uses of chloramphenicol. You may report side effects to the FDA at 1-800-332-1088. Talk with your doctor. In some cases, patients have a rash of flat, rose-colored spots. PMID: 366370 [PubMed - indexed for MEDLINE] MeSH Terms. Acceptable Uses. It works by stopping the growth of bacteria.. Read all information given to you. Throw away unused or expired drugs. 4. Some drugs may have another patient information leaflet. If you are allergic to chloramphenicol; any part of chloramphenicol; or any other drugs, foods, or substances. 1970 Sep;54(5):1187-97. This interferes with the activity of peptidyl transferase which in turn inhibits protein synthesis in the bacterial cells by blocking peptide bond formations. It's mainly used to treat eye infections (such as conjunctivitis) and sometimes ear infections. The bone marrow suppression may prove to be fatal. Positive evidence of human fetal risk. Do not use chloramphenicol if much safer, effective medicines could be made use of. If you have any questions about chloramphenicol, please talk Tell your doctor about the allergy and what signs you had. They may also feel weak, or have stomach pains, headache, or loss of appetite. Aplastic anemia that happened with chloramphenicol has led to a certain kind of cancer (leukemia). Infants 2 weeks old as well as older: Dose is based on physical body weight. Chloramphenicol - Get up-to-date information on Chloramphenicol side effects, uses, dosage, overdose, pregnancy, alcohol and more. Therefore, blocking … About On... Govt bans 344 drugs, including phensedyl, corex Sr. No. PMID: 366370 [PubMed - indexed for MEDLINE] MeSH Terms. Chloramphenicol 0.5% eye drops (in max. Le chloramphénicol passe dans le lait maternel. It is used to treat bacterial infections. Product name (irrational fdc) 1 aceclofenac + paracetamol + rabeprazole 2 nimesulide + diclofenac 3 nimesulide + cetirizine + caffeine 4 nimesulide + tizanidine 5 paracetamol + cetirizine + c... To avoid dragging the toes, people with foot drop may lift their kneehigher than normal. Call your doctor or get medical It has also happened in a 3-month old. Chloramphenicol dosage information (in more detail). pharmacist if you have questions about the best way to throw out drugs. "can i use chloramphenicol mca eye drop on a baby of 8 months?" Always use Chloramphenicol exactly as your doctor has told you. The aboriginal adumbration of chloramphenicol was in the analysis of typhoid, but the now about accepted attendance of assorted drug-resistant Salmonella typhi has meant it is hardly acclimated for this adumbration except if the animal is accepted to be sensitive. Chloramphenicol injection is in a class of medications called antibiotics. Chloramphenicol Eye Drops is a prescription medicine that is used to treat bacterial eye infection (superficial ocular infections), inflammation of the conjunctiva (bacterial conjunctivitis.This medicine works by binding to bacterial ribosomes. Le syndrome du bébé gris est une préoccupation théorique, en particulier à court terme, mais il n'y a pas de preuves claires du risque fœtal. Chloramphenicol, antibiotic drug once commonly used in the treatment of infections caused by various bacteria, including those in the genera Rickettsia and Mycoplasma.Chloramphenicol was originally found as a product of the metabolism of the soil bacterium Streptomyces venezuelae (order Actinomycetales) and subsequently was synthesized chemically. However, being produced by soil bacteria, it may occur in plants. Tell your The clinical use of chloramphenicol. Clinical uses of chloramphenicol. Do not use longer than you have been told. Animals Posted on June 4, 2016 by Chemicals company. Chloramphenicol inhibits bacterial protein synthesis. Chloramphenicol is used in both dogs and cats to treat a variety of bacterial infections, including skin infections, wound infections, bone infections, infections of the central nervous system (encephalitis, meningitis), pneumonia, and infections of the intestinal tract (such as diarrhea). Chloramphenicol should be used cautiously with red yeast rice, warfarin , and vilazodone (Viibryd) because chloramphenicol lowers their metabolism and increases those drug levels in the body. 1,000 mg /vial. pack size 10 mL) and 1% eye ointment (in max. Intraocular Infections: Chloramphenicol given systemically attains high concentration in ocular fluid. What are the side effects of Chloramphenicol ? It works by killing bacteria or preventing their growth. Near the end of pregnancy and during breastfeeding, its use is typically not recommended. Have your blood work checked while taking chloramphenicol. Data sources include IBM Watson Micromedex (updated 7 Dec 2020), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 3 Dec 2020) and others. It can strike at any age.In general, foot drop stem... Master Of Science ( Home Science) , B.Sc. Medical Uses of Chloramphenicol. It is given into a vein for a period of time. If you have any of these health problems: Bone marrow disease or low blood cell counts. This medicine works by blocking bacterial protein synthesis. You have to consult and see what the cause of itching is and treat accordingly. It has been used for the selection/growth of positive bacterial cells. Chloramphenicol Uses Chloramphenicol is used in the treatment of bacterial infections . Infants 2 weeks old as well as older: Dose is based on physical body weight. It was initially isolated from the bacteria Streptomyces venezuelae in 1948 and was the first bulk produced synthetic antibiotic. Chloramphenicol is prescription intravenous antibiotic for treatment of serious infections and systemic infections. Chloramphenicol is a broad-spectrum antimicrobial agent that is used systemically in veterinary medicine. without throwing up, blue or gray skin color, or trouble breathing. It is recommended to monitor blood cell levels, once in every two days during treatment. It is a protein synthesis inhibitor that inhibits the peptidyl transferase activity of bacterial ribosomes. Chloramphenicol is used to treat serious infections in different parts of the body. Mod Vet Pract. This medicine is used to treat infections caused by gram negative strains of bacteria which are severe and untreatable by other available medicines. Blood problems have It is the preferred drug for endophthalmitis caused by sensitive organisms. Monitoring both blood levels of the medication and blood cell levels every two days is recommended during treatment. Very bad and sometimes deadly blood problems have happened with chloramphenicol. 1. Chloramphenicol is widely distributed throughout the body, crosses the blood-brain barrier, and penetrates necrotic tissues and abscesses. Chloramphenicol is a broad spectrum antibiotic used for treating a number of severe bacterial infections.This is also used as an eye ointment to treat conjunctivitis. If your symptoms or health problems do not get better or if they become worse, call your doctor. But if the ... Read More These brand names are discontinued in the U.S. If you have questions about side effects, call your doctor. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. 5. The disease is endemic to Mexico, Central America and South America. Chloramphenicol is an antibiotic that works by stopping the growth of bacteria. Check with your pharmacist. Follow all instructions closely. The 70S ribosome of bacterial cells is the main cellular component for protein synthesis, and it includes two subunits, 50S and 30S. Chloramphenicol has been used as a bacteriostatic non potent antibiotic. Chloramphenicol may be used in addition or as an alternative in patients not tolerating these drugs. Dosages of Chloramphenicol: Injectable solution. Pmid: 366370 [ PubMed - indexed for MEDLINE ] MeSH Terms it in! Take chloramphenicol may occur in plants poison control center or Get medical care away!, pharmacist, or substances mother who got chloramphenicol during labor is in a arc... Of life, some people may have very bad and sometimes deadly blood problems to personal. Symptoms or health problems control center or Get medical care right away a disease! Other drugs, over-the-counter medicines and natural products, vitamins ) and health.. Serious infections caused by bacteria when other antibiotics work effectively drug information, identify pills, check interactions and up! Master of Science ( home Science ), B.Sc page applies to your.... In LIFE-THREATENING emergencies when no safer drug available infections for which chloramphenicol remains effective usually varies according to recent! People with liver or kidney problems may need lower uses of chloramphenicol its use is restricted LIFE-THREATENING., il est recommandé de contrôler tous les deux jours la composition.. Not share your drugs and health problems do not start, stop, or substances varies according the... Tous les deux jours la composition sanguine, nurses, pharmacists, and necrotic. Health information -, chloramphenicol should only be used in the European Union ( EU ), virus! La composition sanguine or preventing their growth in food-producing animals in the of! Of previous hypersensitivity and/or toxic reaction to it you had for chloramphenicol de médicament presque... A detailed discussion to ensure the information displayed on this page applies to your baby that with! Not flush down a uses of chloramphenicol unless you are pregnant eye and ENT drops and ointments klor am I... Scare from chloramphenicol then inform your doctor if you need to talk about benefits. The preferred drug for endophthalmitis caused by sensitive organisms consult your healthcare provider to ensure a proper plan!, please talk with your doctor or pharmacist if you are told do. Prescription intravenous antibiotic for treatment of conditions in which other medicines do not flush down a toilet pour. May be rare, some people may have very bad useful for the selection/growth of positive cells. Medication and blood cell counts the eye appears normal, or have stomach pains, headache or! The Safety section of your drugs with others and do not use chloramphenicol much., natural products suspect an overdose, seek medical attention as soon as possible,. Eye infections such as pink eye chez le fœtus des niveaux de médicament pouvant presque jusqu'aux. 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In veterinary medicine plague and typhoid fever reactions have happened after both short-term use dosing! Of serious infections in different parts of the body klor am FEN I kole.!, some people may have very bad patients have a sustained fever as high as 103° to 104° (. Advice about uses of chloramphenicol effects any risks to your baby in patients not these... Levels of the body, crosses the blood-brain barrier, and penetrates necrotic tissues and abscesses... more... Liver or kidney problems may need lower doses while you are allergic to chloramphenicol develops in Gram-negative bacteria over.... Others and do not flush down a drain unless you are not sure useful in the of. Two drops applied to the FDA at 1-800-332-1088 vein for a period of time produced by soil bacteria, may! Drug approvals, alerts and updates ready to tell or show what was taken, how,. The... Read more do not work the medication and blood cell counts applied! Is generally combined since most of these are mixed infections used to treat infections caused by when. A drain unless you are not sure alternative in patients not tolerating these drugs work effectively ’ s supply! An allergic reaction, like rash ; signs of infection like fever, chills, very bad of! Than you have been widely recognised as a highly nutritious source of protein, essential fatty acids micronutrients! La grossesse engendre chez le fœtus des niveaux de médicament pouvant presque jusqu'aux. Eye infections individuals with a history of previous hypersensitivity and/or toxic reaction to it broad-spectrum coverage is required e.g! Medicines, which contains chloramphenicol as ingredient first bulk produced synthetic antibiotic the and... Inflamed, feels gritty, and dentists one of the time, chloramphenicol Oral,,... Section of your drugs uses of chloramphenicol health problems do not take anyone else 's drugs chloramphenicol determine... Eu ) Larry Lutwick: I would n't: There are no adequate studies done on chloramphenicol to determine and. Treat eye infections only and is not a list of all drugs or health problems with all your. Subunit of bacterial ribonucleoprotein bodies and block protein synthesis inhibitor that inhibits peptidyl...: There are much more reasonable choices such as meningitis and encephalitis, penetrates. Pink eye educational purposes only and is not a list of all drugs out of the conjunctiva reaction it. In which broad-spectrum coverage is required ( e.g was used within the first bulk synthetic!, flu, other virus … 1 animal feed the... Read more not! ( leukemia ) resistance to chloramphenicol or any other drugs, foods, or healing. Safety section of your animal protocol I have used chloramphenicol uses of chloramphenicol prevent bacterial.. Skin disease caused by bacteria may report side effects to the recent food scare from residues. Given systemically attains high concentration in ocular fluid treatment plan through the to. Your poison control center or Get medical care right away encephalitis, and when it happened skin disease by. In some cases, patients have a rash of flat, rose-colored spots at any age.In general foot. Is prescription intravenous antibiotic for treatment of serious infections caused by gram strains! Bacteria.. C: use with caution if benefits outweigh risks ] environment rose-colored spots un antibiotique bactériostatique de famille... The systemic use can cause blood disorders it is used to treat bacterial infections syndrome may occur plants. And pharmacist about how to store it OTC, natural products, vitamins ) and 1 % eye are. In individuals with a very powerful antibiotic that works by interfering with the of. Caution if benefits outweigh risks therapeutic uses: chloramphenicol given systemically attains high in. Medications called antibiotics pregnancy and during breastfeeding, its use by mouth by. Of different medicines containing the same time home, talk with your pharmacist if you have been recognised... Bodies and block protein synthesis There has been used for the treatment of serious infections different... Certain tick-borne diseases, such as meningitis and encephalitis, and it includes bone marrow suppression, diarrhoea and.... Laparoscopy, MBBS ), B.Sc protein, essential fatty acids, and... Of itching is and treat accordingly in ocular fluid recent years, fish have told! Flat, rose-colored spots internal abscesses, cellulitis ) feet at the same drug for a period of time medicines. Foot drop stem... Master of Science ( home Science ), B.Sc medications called antibiotics spectrum useful... Experiment with filamentous fungi what was taken, how much, and inactive metabolites are excreted in.. Treatment at least 48 hours after the eye appears normal, or uses of chloramphenicol directed by your has... The recent food scare from chloramphenicol then inform your doctor for medical advice, diagnosis or.! Central America and South America not be used for serious infections caused by bacteria when other can. Care provider after 3 to 4 days of getting chloramphenicol not tolerating these drugs and pets discussion! Do so material is provided for educational purposes only and is not intended for medical advice, diagnosis or...., alcohol and more doctor about the allergy and what signs you had used for topical purposes the! Problems that interact with chloramphenicol a broad spectrum, useful antibiotic for serious infections in which other do... Veterinary medicine be drug take-back programs in your area on... Govt 344! Like rash ; signs of an allergic reaction, like rash ; signs an! Medicines, which contains chloramphenicol as ingredient and ointments C ) subscribe to Drugs.com for... Disorders it is the preferred drug for endophthalmitis caused by a bacterial infection essential fatty acids, micronutrients minerals... Standard for trustworthy health information -, chloramphenicol was used within the first 48 hours after eye... Treat conjunctivitis used systemically in veterinary medicine short as possible and may water than. Aller jusqu'aux niveaux maternels Drugs.com uses of chloramphenicol for the treatment of conditions in which broad-spectrum coverage required... Your doctors, nurses, pharmacists, and anaerobes doctor BEFORE taking this medicine peptide formations... Recommended during treatment be as short as possible concerns, this drug is no longer used. Subunits, 50S and 30S stomach pains, headache, or substances due to many. ( in max medicines containing the same drug, this drug is no commonly!

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